• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Peer Review Process
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
Journal of the Medical Research Institute
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 46 (2025)
Issue Issue 1
Volume Volume 45 (2024)
Volume Volume 44 (2023)
Volume Volume 43 (2022)
Volume Volume 42 (2021)
Volume Volume 41 (2020)
Volume Volume 40 (2019)
Volume Volume 39 (2018)
Volume Volume 38 (2017)
Volume Volume 37 (2016)
Volume Volume 36 (2015)
Mohamed, A., Daabis, R., Mahgoub, M., Eldeeb, M., Magour, G., Badran, E. (2025). Role of Biochemical And Hematological Markers in Predicting COVID-19 Severity and Mortality Among Egyption Patients. Journal of the Medical Research Institute, 46(1), 26-35. doi: 10.21608/jmalexu.2025.349076.1044
Abeer Ahmed Mohamed; Rasha Galal Daabis; Mohamed Anwar Mahgoub; Mona Kamal Eldeeb; Gehan Mahmoud Magour; Eman Mahrous Badran. "Role of Biochemical And Hematological Markers in Predicting COVID-19 Severity and Mortality Among Egyption Patients". Journal of the Medical Research Institute, 46, 1, 2025, 26-35. doi: 10.21608/jmalexu.2025.349076.1044
Mohamed, A., Daabis, R., Mahgoub, M., Eldeeb, M., Magour, G., Badran, E. (2025). 'Role of Biochemical And Hematological Markers in Predicting COVID-19 Severity and Mortality Among Egyption Patients', Journal of the Medical Research Institute, 46(1), pp. 26-35. doi: 10.21608/jmalexu.2025.349076.1044
Mohamed, A., Daabis, R., Mahgoub, M., Eldeeb, M., Magour, G., Badran, E. Role of Biochemical And Hematological Markers in Predicting COVID-19 Severity and Mortality Among Egyption Patients. Journal of the Medical Research Institute, 2025; 46(1): 26-35. doi: 10.21608/jmalexu.2025.349076.1044

Role of Biochemical And Hematological Markers in Predicting COVID-19 Severity and Mortality Among Egyption Patients

Article 3, Volume 46, Issue 1, March 2025, Page 26-35  XML PDF (895.21 K)
Document Type: Original Article
DOI: 10.21608/jmalexu.2025.349076.1044
View on SCiNiTO View on SCiNiTO
Authors
Abeer Ahmed Mohamed* 1; Rasha Galal Daabis2; Mohamed Anwar Mahgoub3; Mona Kamal Eldeeb1; Gehan Mahmoud Magour1; Eman Mahrous Badran1
1Department of Chemical Pathology, Medical Research Institute, Alexandria University, Egypt
2Department of Chest Diseases, Faculty of Medicine, Alexandria University, Egypt
3Department of Microbiology, High Institute Of Public Health, Alexandria University, Egypt
Abstract
Coronavirus Disease 2019 (COVID-19) has significantly impacted global health, leading to severe disease and high mortality rates. Understanding the severity of COVID-19 and its associated mortality is crucial for managing the pandemic and developing effective treatments.Patients can present with a wide array of symptoms. Laboratory investigations of these patients for several biochemical and hematological tests are routinely requested. Here we wanted to evaluate the utility of procalcitonin (PCT), ferritin, D-Dimer, interleukin 6 (IL-6) , C-reactive protein, total lactate dehydrogenase (LDH) activity, lymphoctic count and neutrophils/ lymphocytes ratio in predicting severity and mortalitity of COVID-19 infection.

This study was undertaken at Alexandria university main hospital representing 180 COVID-19 RT-PCR positive patients after approval of the Ethical Committee of the Medical Research Institute and exclusion of patients with chronic lung diseases, diabetes mellitus, renal failure, hypertension, malignancy and previous history of chemotherapy and radiotherapy. The patients were grouped according to National Institutes of Health (NIH) guidelines; as mild to moderate (n=80) and severe to critical (n= 100). All routine clinical chemistry analysis was performed as part of routine baseline assessment. Biomarkers of inflammation and infection were tested via the measurement of CRP, IL-6, PCT and ferritin. In addition to urea , creartinine, AST, ALT, LDH and complete blood count as well as INR and D-Dimer.
Keywords
COVID-19; SARS-CoV-2; interleukin-6; D-dimer; procalcitonin
Main Subjects
Research articles (original articles)
Statistics
Article View: 138
PDF Download: 67
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.