Effective Management of Acute Aluminum Phosphide Poisoning in Pregnancy: A Case Study of Dual Therapy Efficacy and Collaborative Care

Document Type : Case Report

Authors

1 Forensic medicine and clinical toxicology department, Faculty of medicine, Alexandria University, Alexandria, Egypt

2 Clinical Research Administration, Alexandria Directorate of Health Affairs, Egyptian Ministry of Health and Population, Alexandria, Egypt

3 Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt

4 Directorate of Health Affairs in Buhaira-Clinical Research Department, Ministry of Health and Population, Damanhur, Egypt

Abstract

Aluminum phosphide (AlP) poisoning is a significant public health concern, particularly in developing countries where it is easily accessible. This case report discusses the successful management of acute AlP poisoning in a pregnant woman at 28 weeks gestation. Initially presenting with vomiting and abdominal pain and discomfort, the patient remained stable throughout. Metabolic acidosis, identified through arterial blood gas analysis, prompted bicarbonate administration. The application of dual therapy with N-acetylcysteine (NAC) and Coenzyme Q10 (CoQ10) effectively countered oxidative stress, contributing to the patient's stabilization. Collaborative interdisciplinary care played a crucial role in ensuring the well-being of both the mother and fetus, ultimately resulting in a favorable outcome upon discharge. This case highlights the effectiveness of therapeutic interventions and underscores the pivotal importance of interdisciplinary cooperation in managing acute AlP poisoning. Such instances reinforce the significance of a rapid and coordinated response to mitigate the potentially fatal consequences of poisoning incidents.

Keywords

Main Subjects

Files

Share

How to cite

Statistics